Cytotoxic neolignans from the traditional Chinese medicine Daphniphyllum macropodum Miq.
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چکیده
منابع مشابه
Yuzurimine from of Daphniphyllum macropodum Miq.
The title compound, C(27)H(37)NO(7), is a Daphniphyllum alkaloid isolated from a branch of Daphniphyllum macropodum Miq. All of the five-membered rings adopt envelope conformations while the six- and seven-membered ring adopt chair conformations. Classical inter-molecular O-H⋯O and weak C-H⋯N hydrogen bonds are present in the crystal structure.
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Five new alkaloids, daphnicyclidins M and N (compounds 1 and 2) and calyciphyllines Q-S (compounds 3-5), along with four known ones, paxiphylline C (6), macropodumine B (7), macropodumine C (8) and daphnicyclidin A (9) were isolated from the stem bark of Daphniphyllum macropodum. Calyciphylline Q (3) is the first calyciphylline A derivative possessing a double bond between C-18 and C-19. Their ...
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Lida Teng, BSc, is a PhD student at the Centre for Pharmacognosy and Phytotherapy, School of Pharmacy, University of London; Debbie Shaw, BSc, is a research scientist at the Medical Toxicology Unit, Guy’s and St Thomas’ Hospital NHS Foundation Trust, London; and Joanne Barnes, PhD, MRPharmS, is associate professor in herbal medicines at the School of Pharmacy, Faculty of Medical and Health Scie...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2017
ISSN: 2046-2069
DOI: 10.1039/c7ra09569d